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產(chǎn)品規(guī)格
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BN41764R-50ul
50ul
￥1486.00
交叉反應(yīng)：Human(predicted:Rabbit,Horse,Dog,Rat,Mouse) 推薦應(yīng)用：WB,Flow-Cyt,ELISA
BN41764R-100ul
100ul
￥2360.00
交叉反應(yīng)：Human(predicted:Rabbit,Horse,Dog,Rat,Mouse) 推薦應(yīng)用：WB,Flow-Cyt,ELISA
BN41764R-200ul
200ul
￥3490.00
交叉反應(yīng)：Human(predicted:Rabbit,Horse,Dog,Rat,Mouse) 推薦應(yīng)用：WB,Flow-Cyt,ELISA
產(chǎn)品描述
| 英文名稱 | SLC10A1 |
| 中文名稱 | 鈉離子/牛磺膽酸共轉(zhuǎn)運蛋白抗體 |
| 別 名 | Na+/taurocholate Cotransporting Polypeptide; Na(+)/bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na / bile acid cotransporter; Na / taurocholate transport protein; Na(+)/taurocholate transport protein; NTCP; NTCP1; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1; Slc10a1 protein; Slc10a1; SBACT; SLC10A1; NTCP_HUMAN. |
| 研究領(lǐng)域 | 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)運蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, (predicted: Mouse, Rat, Dog, Horse, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=1μg /test ICC=1:100-500 IF=1:100-500 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 38kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NTCP:21-120/349 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | Sodium/bile acid cotransporters are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids, one absorbing from the intestinal lumen, the bile duct, and the kidney with an apical localization(SLC10A2; MIM 601295), and the other being found in the basolateral membranes of hepatocytes (SLC10A1).[supplied by OMIM] Function: The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Liver and kidney Similarity: Belongs to the sodium:bile acid symporter family. SWISS: Q14973 Gene ID: 6554 Database links: Entrez Gene: 6554 Human Entrez Gene: 20493 Mouse Omim: 182396 Human SwissProt: Q14973 Human SwissProt: O08705 Mouse Unigene: 952 Human Unigene: 341781 Mouse Unigene: 9913 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. NTCP（鈉離子/?；悄懰峁厕D(zhuǎn)運蛋白）(鈉離子-?；悄懰峁厕D(zhuǎn)運多肽)Na+/taurocholate Cotransporting Polypeptide是 肝臟的膽汁酸鹽吸收主要是鈉離子依賴性轉(zhuǎn)運子NTCP介導(dǎo)的，主要吸收?；悄懰?，是肝細(xì)胞特有的一種轉(zhuǎn)運載體，分布在肝細(xì)胞基側(cè)膜在肝小葉和肝的腺泡表達(dá)較多。 有學(xué)者認(rèn)為：NTCP是乙肝病毒的細(xì)胞表面受體分子，是HBV和HDV的功能受體，這些研究將有待于科研人員的進(jìn)一步證實。 |
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